Intravenous immunoglobulin therapy for severe Clostridium difficile colitis
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چکیده
منابع مشابه
Intravenous immunoglobulin therapy for severe Clostridium difficile colitis.
BACKGROUND Many individuals have serum antibodies against Clostridium difficile toxins. Those with an impaired antitoxin response may be susceptible to recurrent, prolonged, or severe C difficile diarrhoea and colitis. AIMS To examine whether treatment with intravenous immunoglobulin might be effective in patients with severe pseudomembranous colitis unresponsive to standard antimicrobial the...
متن کاملIntravenous Immunoglobulin in the Treatment of Severe Clostridium Difficile Colitis
Intravenous immunoglobulin (IVIG) has been utilized in patients with recurrent and refractory Clostridium difficile colitis. It is increasingly being used in patients with initial clinical presentation of severe colitis. Herein, we report a case of severe C. Difficile colitis successfully treated with IVIG with a review of the medical literature to identify the optimal timing and clinical chara...
متن کاملIntravenous immunoglobulin therapy for severe Clostridium diYcile colitis
Background—Many individuals have serum antibodies against Clostridium difficile toxins. Those with an impaired antitoxin response may be susceptible to recurrent, prolonged, or severe C diYcile diarrhoea and colitis. Aims—To examine whether treatment with intravenous immunoglobulin might be eVective in patients with severe pseudomembranous colitis unresponsive to standard antimicrobial therapy....
متن کاملIntravenous immunoglobulin for resistant Clostridium difficile infection.
Clostridium difficile (CD)-associated diarrhoea and colitis may relapse in up to 20% of treated patients. We present a patient who failed to respond over a 6-month period to treatment either singly or in combination with metronidazole, vancomycin, rifampicin, cholestyramine and probiotics. Her diarrhoea rapidly resolved after a 3-day course of intravenous immunoglobulin. This treatment may comp...
متن کاملClostridium difficile colitis
Bacteriology and Pathogenesis Clostridium difficile is a Gram-positive sporeforming anaerobic bacillus, which is found in the stool flora of 25-80% of healthy infants but rarely in the stool of healthy adults and children over the age of 12 months. Ingested spores of C. difficile survive the gastric acid barrier and germinate in the colon. Colonization of the adult intestinal tract occurs when ...
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ژورنال
عنوان ژورنال: Gut
سال: 1997
ISSN: 0017-5749,1468-3288
DOI: 10.1136/gut.41.3.366